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Hereditary Peripheral Neuropathy

At Nupera, we believe that understanding hereditary peripheral neuropathy is the first step toward lasting relief. While your genes may play a role, they don’t have to dictate your future. With the right support, you can protect and nourish your nerves, naturally and effectively.
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What Is Hereditary Peripheral Neuropathy?

Hereditary peripheral neuropathy is a genetic condition that affects the nerves outside the brain and spinal cord. Unlike neuropathies with unknown causes, this type is inherited—passed down through family lines.
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The most well-known form is Charcot-Marie-Tooth disease (CMT), but there are many subtypes, each affecting the nerves differently. These conditions may damage the motor nerves (controlling movement), sensory nerves (controlling sensation), or both, leading to symptoms like weakness, tingling, and pain, especially in the hands and feet.
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Some individuals have hereditary motor sensory neuropathy (HMSN), while others may experience hereditary sensory and autonomic neuropathy (HSAN), which can also disrupt functions like digestion or blood pressure control.

Common Signs & Symptoms of Hereditary Peripheral Neuropathy

Symptoms often begin subtly but can progress over time. The most common signs include:

  • Gradual muscle weakness in legs, feet, hands, or arms
  • Difficulty walking or frequent tripping
  • High arches or flat feet (a common physical sign of CMT)
  • Numbness or tingling in the extremities
  • Loss of coordination or balance
  • Muscle wasting in the lower legs or hands
  • Autonomic symptoms in HSAN, such as blood pressure instability, bladder issues, or impaired sweating

Even within the same family, symptoms can vary widely, making early recognition and personalized care essential.

What Causes Hereditary Peripheral Neuropathy?

These neuropathies are caused by mutations in specific genes responsible for nerve structure and function. When those genes malfunction, the protective covering around nerves (myelin) or the nerve fibers themselves (axons) deteriorate, leading to impaired signal transmission.
Some common inherited neuropathies include:

  • Charcot-Marie-Tooth Disease (CMT) – The most prevalent form
  • Hereditary Sensory and Autonomic Neuropathy (HSAN)
  • Hereditary Neuropathy with Liability to Pressure Palsies (HNPP)

Diagnosis often involves genetic testing, nerve conduction studies, and family history analysis.

Risk Factors for Hereditary Neuropathy

The key risk factor for hereditary peripheral neuropathy is a family history of nerve-related disorders. Other considerations include:

  • Being born to a parent with a known genetic mutation
  • Symptoms of neuropathy appearing in early life
  • Having siblings or close relatives with similar neurological conditions
  • Genetic conditions that affect mitochondrial or metabolic function

While you can't change your genetics, you can change how you support your nerves—and that's where Nupera can help.

Best Natural Treatment for Hereditary Peripheral Neuropathy

What makes Nupera’s innovative treatment unique?

You may not be able to change your genes, but you can take steps to manage your symptoms and protect your nerves.

Step 1: NuperaPulse

  • Delivers mechanical energy using a handheld wand
  • Boosts blood flow and oxygen delivery to damaged nerves
  • Prepares tissues for deeper healing with NuperaWave

Step 2: NuperaWave

  • Uses focused ultrasound to stimulate nerve regeneration
  • Targets the myelin sheath and axons for improved conductivity
  • Enhances circulation and supports natural immune repair

This noninvasive approach helps restore nerve health—naturally and effectively.

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Ready to Reclaim Control?

If you or a loved one has been diagnosed with hereditary peripheral neuropathy, Nupera is here to help. Our holistic approach isn’t about masking symptoms—it’s about helping you live a fuller, more vibrant life despite the diagnosis.
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Let’s build a plan for stronger nerves, steadier movement, and greater confidence—starting today.
Start Your Healing Journey Now

Experience lasting relief from peripheral neuropathy with Nupera's innovative 2-step treatment that promotes nerve healing and regeneration.

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Pain Management of Diabetic Peripheral Neuropathy

You may have been advised to try the following to keep the pain of Diabetic peripheral neuropathy under control:

  • Blood Sugar Control: Maintaining stable blood sugar levels can help slow the progression and reduce symptoms.

  • Medications: Over-the-counter pain relievers like acetaminophen or ibuprofen. Diabetic peripheral neuropathy drug options, such as anticonvulsants (e.g., gabapentin) or antidepressants (e.g., amitriptyline). Topical treatments, like capsaicin cream or lidocaine patches.

  • Physical Therapy: Exercises to improve strength and balance, reducing stress on affected nerves.

  • Alternative Therapies: Acupuncture, biofeedback, or transcutaneous electrical nerve stimulation (TENS) may help alleviate pain.

  • Lifestyle Adjustments, including comfortable footwear to protect feet and stress management through relaxation techniques or counseling. Avoiding smoking and limiting alcohol, as they can worsen nerve damage.